28 October, 2008

Green-Lipped Mussels Omega-3 Oils Join Moxxor, NaturalNews

by Mike Adams

(NaturalNews) The world of omega-3 superfoods just experienced a breakthrough. A new company called "Moxxor" has introduced a marine omega-3 oil supplement derived from green-lipped mussels grown and harvested in the aquaculture farms of New Zealand. This story explains why I'm endorsing this company, its products and its direct-sales compensation plan, how your support of Moxxor benefits NaturalNews, and how I came to be a product formulation advisor to the Moxxor organization.

As you read this, remember: I'm a skeptic when it comes to direct sales companies. I've been approached by dozens over the years, and I've turned them all down. And why? Because most of the products I've seen in direct sales companies aren't very impressive. Few companies operate with the kind of integrity I demand of companies I choose to publicize. But as you'll learn here, Moxxor is truly a unique company, and one that's positioned to take off in 2009.

But to explain why, I first have to tell you about Noel.

Noel Turner, fisherman turned Moxxor CEO

Noel is the most high-energy New Zealander I've ever met. He waltzed right over to me after I finished an on-stage presentation to 500 people about South American rain forest herbs and gleefully introduced himself. Pumping my hand and grinning from ear to ear, he said his name was Noel Turner, and he was starting a health supplement network marketing company that would become a billion-dollar enterprise.

Sure. Right. Whatever. I hear it all the time. "I'm the ultimate skeptic on health products," I told him. "And I've only recommended one network marketing company, and that's the Amazon Herb Co." I'm not even a distributor for that company, by the way. All my recommendations for AHC have been on a 100% volunteer basis.

That didn't break his grin, not even for a second. He said he was a self-made millionaire, and he and his twin brother (Johnny) had made their fortune in aquaculture. Specifically, they farmed green-lipped mussels in the fjords of New Zealand.

Green-lipped mussels? Visions of clammy Vulcans came to mind. I didn't really know what green-lipped mussels were, and I frankly wasn't that interested at the time. Noel didn't push the issue; he just flicked a business card into my hand, enthusiastically shook it twice for good measure, and said I'd be hearing from him.

Fast forward twelve months.

One day I get an interesting package in the mail. Upon opening it, I discover it contains six bottles of nutritional supplements made from -- guess what? -- green-lipped mussel oil.

Suddenly I remembered the conversation... New Zealand, Noel Turner, ah yes, it's all making sense now. A note in the package said, "Try Moxxor, Mike. We're launching in four months. This is the nutritional supplement you've been waiting for. - Noel Turner."

Trying Moxxor for myself

Since Noel had gone through the trouble of sending me the product, I decided to at least do some research and see what he could possibly be so excited about. So I turned to Google and our own NaturalNews Naturalpedia, where I found numerous references to green-lipped mussel oil.

It turns out green-lipped mussel oil has remarkable anti-inflammatory properties. While I've been recommending astaxanthin and other omega-3 oils for their anti-inflammatory properties, this looked to me like something else I could recommend to readers who wanted to take a nutritional approach to supporting the body's healthy response to inflammation in a way that's safer and far less expensive than pharmaceuticals. I also knew omega-3s were great for supporting healthy moods and healthy neurological development in children. The Moxxor product also contains a healthy dose of DHA, the fatty acid linked to healthy neurological function in children (it's found naturally in breast milk).

Further research also revealed this oil to be extraordinarily good at supporting skin health, heart health and healthy circulation -- not surprising, given all the incredible news about omega-3 oils we've been reporting on NaturalNews for nearly five years. You can see our online presentation about Moxxor, by the way.

So I decided to try it. I popped a couple of the small Moxxor pills into my mouth and headed to the gym for a challenging workout.

Putting Moxxor to the test

That's where I gave my body a real workout: Pilates, Capoeira, jumping rope, poi spinning, pushups and handstands... I did Spiderman crawls across the floor, dynamic contraction strength training and weird floor exercises I can't even begin to describe. I went home knowing I'd be sore and inflamed the next day. (My lower back usually takes the worst hit from a day of exercise like that. It's typically sore for days...)

To my great astonishment, I woke up the next morning an hour early. I felt wide awake, full of energy and ready to take on the day. What was up with that? I actually wanted to sleep another hour, but since I was up, I decided to start juicing and get an early start on the morning.

That's when I realized my back didn't hurt. It wasn't sore at all. It wasn't all crunched up like it usually is after a hard workout. And I didn't even take any astaxanthin, either! Could this Moxxor green-lipped mussel oil actually work so quickly to ease my pain? To this day, I can't make that claim with absolute certainty, but in my mind, Moxxor has without question supported my body's ability to respond to the stress of exercise in a healthy, balanced way!

This experience reinforced my respect for the potential nutritional power of green-lipped mussel oil. In all my years of covering nutritional products, I've only found two products that contributed so much to my physical performance (including exercise recovery): Astaxanthin and Moxxor green-lipped mussel oil. It's interesting that they both come from the ocean, isn't it?

Connecting with the Turners

It wasn't long before I picked up the phone and called back Noel Turner. I admitted I was really impressed with the effects of the product, but for me to recommend something like this (especially given that it's a direct sales company), I would have to check him out in a lot more detail. (Due diligence is a very important part of my work as a natural health journalist.)

I needed to know the founders, how they lived day to day, what's their philosophy, do they have business experience, is the product really pristine, what's their dedication to environmental protection, and so on.

"Well fly out to California and visit our headquarters," Noel said. "You can see the whole operation and meet the family." He offered to pick me up at the airport in his "Moxxor mobile" (which was a luxury Mercedes that goes really, really fast, I later discovered...)

At this point, I was intrigued enough to get on a plane and just go. I figured, well maybe there's a chance this is not the real deal, but there's also a possibility this is something truly amazing, and it's my job to check these things out for my readers, so I'm going.

And I did.

Speeding along in the Moxxor mobile

At the airport in Orange County, Noel and his brother Johnny met me at the curbside pickup area, driving their luxury Mercedes sedan. I hopped in the back seat and soon discovered Noel's superb high-speed driving skills. (The Mercedes has amazing handling characteristics.)

Seventeen minutes later, we arrived at the $10 million Moxxor building. I was invited upstairs, to the corporate offices, where I met the top management team. From there, we sat down for several hours of questions and answers, all powered by superfoods and organic produce. (Noel drinks LivingFuel superfood, by the way. He learned about it on NaturalNews! He also likes DragonHerbs.com products, which are high-end Chinese Medicine formulas.)

Between you and me, I grilled these guys. Taking the skeptic's point of view, I asked them all the tough questions: What's the CO2 footprint of your product? (Try that on some business people sometime... it'll leave them scratching their heads.) How are the green-lipped mussels fed? How are they harvested? What's the highest temperature reached during processing? Are there any chemical solvents used in the extraction process? What scientific research do you have backing the health benefits of green-lipped mussel oil? What are the exact milligrams of each of the three ingredients in the formula?

Without going into all the detailed answers here (there's another place for that), I can share that Moxxor passed with flying colors. I was genuinely impressed by all the answers they provided. They're on-board with the philosophy of doing well by doing good, and they have a clear, inspired vision of bringing healthy living to millions of adults, children and senior citizens, many of whom are dangerously deficient in fish oils, omega-3 oils and vitamin D. (And green-lipped mussel oil, in my view, is a phenomenal combination of all three!)

I said, "Okay, well what's next? You want me to write about your company, right?" Because that's what companies usually want me to do. And it's my job to sort out the junk companies from the quality companies. I could already tell this was a rare find -- a quality company that had a bright future.

But they had other plans.

The Moxxor / NaturalNews partnership

Instead of asking me to write about the company, they invited me to be part of the product formulation advisory board! I was asked to offer guidance on future product formulations, just to make sure they stayed at the forefront of the industry and used only the very best ingredients in their products. Zero junk, zero fillers, zero chemicals, that sort of thing.

No problem, I said. I'd love to bring my nutritional knowledge to the table so I can help your company stay at the lead of this industry. The network marketing industry needs more high-integrity companies, especially given all the junk that exists in the marketplace.

That's when they asked that I delay mentioning Moxxor on NaturalNews for a while and that I hold off on publishing any sign-up links on the website until they were good and ready with a sufficient inventory of product.

Sign-up links? I asked them, "What are you talking about? I'm writing about your company as a journalist. Why are you talking about recruitment?"

"Simple," Noel answered, "Because we want to offer NaturalNews a founding, top-level distribution position in the company when it launches."

Starting at the very top

Stop the music for a second. I've made a career out of saying no to nutritional supplement companies, and in doing so, I've established a hard-won reputation for telling the truth about supplements, anti-cancer nutrients and the dangers of pharmaceuticals.

In that process, I've helped many supplement companies become extremely successful. I don't know how many hundreds or thousands of distributors I've helped get involved with the Amazon Herb Co., but I know they come up to me all the time in public and thank me for introducing them. And yet during all that time, I never made a dime from them.

That's when I remembered my 7 Principles of Mindful Wealth. As I've publicly shared in that report, there's no karma in staying poor. What really matters in this modern world when it comes to money is whether you can mindfully earn and redistribute wealth.

If you can do that with ethics, and with the respect for sustainable life on our planet, then you deserve to attract more wealth. The universe wants you to attract more financial resources when you're the right person to decide how to use it. And here I was, in the headquarters of the Moxxor company, being invited by the founders to participate in a potentially huge health-related financial opportunity being put right in my lap. It was also, I realized, something that could eventually replace our existing revenue source on NaturalNews, which is primarily Google.

I also realized that if I could encourage NaturalNews readers to be part of this launch, then I could replace the Google ads (which pay profits to Google) with Moxxor ads that ultimately distribute profits to NaturalNews team members who enroll with Moxxor.

Kind of a no brainer, huh? Let's see: By launching Moxxor on NaturalNews, we could stop sending profits to Google and redirect those profits to NaturalNews readers and NaturalNews health freedom operations... while at the same time eliminating those annoying Google ads that always appear for products we don't even support...

(Keep reading to see how YOU can benefit from the NaturalNews efforts on Moxxor. We have literally put a system in place where NaturalNews readers can receive significant financial benefits from being on the NaturalNews team. It's all explained below...)

When I thought about all the positive implications for NaturalNews, its readers, and the opportunity that had been placed right in front of my nose, for the first time in my life as a natural health journalist, I said YES. I would embrace this company, its products, and this opportunity, but only under certain conditions. They listened as I explained...

I would quit if they ever cheapened the product and filled it with junk. I would not stand for pollution of the environment during product processing, and I emphasized my desire that the gelatin capsules be switched over to plant-based capsules as soon as possible. (I know the cows in New Zealand are pure and all that, but I still wanted to see a commitment to shift towards plant-based capsules in the long term.)

Furthermore, I specifically asked that before the harvest of the green-lipped mussels, the aquaculture fields be blessed with positive intention, and thanks be given to the oceans and Mother Nature for providing such abundance. They not only agreed; Noel invited me to New Zealand to bless the aquaculture fields myself!

I'm flying there in November...

The NaturalNews Moxxor team

Over the last few weeks, I've been working behind the scenes to build the most successful health product direct sales team in the world. Hundreds of health-conscious, eco-conscious people have already joined the NaturalNews Moxxor team (including many N.D.s, M.D.s, chiropractors, herbalists, bodywork practitioners, and more), and we've accomplished a tremendous amount in a short time:

• A phenomenal team of hundreds of distributors in more than 28 states, 4 countries and covering 5 spoken languages. See our directory of our top distributors.

• Weekly LIVE audio events every Tuesday evening (led by myself), plus an archive of each week's audio file that you can download as MP3.

• A high-end, impactful online presentation that can be personalized to each distributor so that the enrollment clicks go directly to them. See this presentation (when you enroll with us, you'll receive a personalized page just for you).

• A series of audio marketing tools and interviews that each distributor can freely burn to audio CDs and hand out to others.

• A support team that can help answer questions and provide information to help NaturalNews team members reach success as quickly as possible.

... and there's more on the way. I'm not going to spill the beans on what else we're about to release for NaturalNews Moxxor team members, but I can confidently tell you this: In the history of network marketing, nobody has ever created the level of authenticity, positive purpose and replication technologies that we now have available for those who decide to join our team. We're combining purpose, products and technology in a way that's simply never been done before.

That's why the NaturalNews Moxxor team delivers a high-integrity product, a generous compensation plan and a pledge to create lasting good with the funds we generate. Everything we do is 100% aligned with our 7 Principles of Mindful Wealth, which describes a set of powerful principles for attracting and redistributing wealth in a mindful way that helps create a better world.

If you'd like to join us in this mission, you can enroll with us.

Once you enroll, you'll be part of the rapidly-growing NaturalNews team, which has already become something of a phenom in professional network marketing circles due to the degree of integrity, technology tools and support we bring to our team members.

Watch our video before enrolling to learn what Moxxor is all about and how you can earn a healthy income stream as a member of our team.

Although I don't have a crystal ball, I think Moxxor could be the next $1 billion health product network marketing company. I can't guarantee it, of course, but all my sense in the health products industry tells me this is going to be wildly successful. I've watched other companies succeed, and I can see that Moxxor has the key ingredients for real long-term success: Honest products, personal integrity and a generous compensation plan that encourages team building. In just the last 30 days, we've see explosive growth just from the early adopters who got on board through my Mindful Wealth email list. Some are already earning respectable incomes with Moxxor, and one woman I know just gave her two-week notice to her employer so she could focus full time on the NaturalNews Moxxor team!

Building a conscious team that stands for truth, health and protecting life
I'm very conscious about the type of team we are building here. The NaturalNews team is right now attracting dedicated, health-conscious people who already live a holistic lifestyle. We want people who eat superfoods, who exercise and who are into protecting life on Earth and supporting good causes. We want people who will commit to a code of ethical principles surrounding money, and who will put their new found wealth to an important application that helps solve the pressing problems in our world.

If this resonates with you, you'll enjoy being part of the NaturalNews Moxxor team. It's not only a phenomenal team filled with intelligent, high-vibration individuals; it's also a team populated with many successful business entrepreneurs who can help show you how to create a healthy income that pays you month after month, year after year. NaturalNews will even help support your success in a multitude of ways!

If you've been looking for good news about health and wealth, I think the universe just brought it to you. Learn about the NaturalNews Moxxor opportunity, and if you'd like to be part of our rapidly-expanding team, get enrolled right now.

In future articles here on NaturalNews.com, I'll be reviewing Moxxor's green-lipped mussel oil and comparing it to other omega-3 oil sources (krill oil, fish oil, flax oil, salmon oil, etc.) In fact, we've planned a whole series of articles on green-lipped mussel oil. And guess what? When you're on the NaturalNews Moxxor team, you can freely post these articles on your own website or blog site, and replace our own enrollment link with YOURS. You have my full permission to do that right now.

I look forward to seeing you on the NaturalNews Moxxor team, and when you try this product yourself, you immediately come to recognize why I'm so excited about this product, this opportunity and this new revenue stream for YOU and US. This is teamwork at its best, and the way in which we have approached this -- sharing leads with team members, distributing free tools, etc. -- demonstrated our integrity and our commitment to helping YOU achieve lasting success as part of the NaturalNews Moxxor team.

24 October, 2008

Excuse Me, That Gas Lowers My Blood Pressure

Dr. Solomon Snyder from Johns Hopkins determined that the embarrassing aroma of flatulence is caused by a gas which lowers blood pressure. The team at Johns Hopkins reported its conclusions in the October 24 edition of the journal ‘Science.’

Over the past twenty years, biologists have been intrigued by the properties of various gases (called gasotransmitters) in signaling a number of functions in the bodies of mammals. You may be familiar with some earlier work. Nitrous oxide is used by many cardiac patients. Gasotransmitters are common in mammals. Findings on the importance of hydrogen sulfide in mice, as this study reports, may have applications in human diseases, such as diabetes and neurodegenerative diseases.

Cells lining the blood vessels produce hydrogen sulfide (H2S). This gas produces the all-too-familiar rotten egg odor when a person breaks wind. This same gas seems to relax the walls of blood vessels, easing hypertension.

Dr. Snyder’s team genetically altered mice so that their cells did not produce an enzyme called cystathionine gamma-lyase (CSE). CSE deficient mice showed reduced H2S levels in their serum, heart, aorta, and other tissues. The non-chimera littermates had higher levels of H2S. The results confirmed the hypothesis that the enzyme was key in tissues’ production of H2S.

Modified mice showed significantly higher blood pressure comparable to serious hypertension in humans. They also had increased plasma homocysteine levels, suspected as a marker for inflammation and higher risk for cardiovascular disease. In addition, L-cysteine levels were lower in the chimera. L-cysteine plays a key role in the immune system and in protecting the liver. Both functions seem to be related to L-cysteine’s role in the production of glutathione. Glutathione levels were also lower in the genetically altered mice.

Scientists dosed the mice with a chemical called methacholine that relaxes normal blood vessels. The CSE-lacking mice’s blood vessels showed little change. Researchers concluded that hydrogen sulfide is a significant for regulating blood pressure.

The researchers note that all animal experiments were conducted in accordance with approved protocols by the Animal Health Care Committee of the University of Saskatchewan, Canada.

The study did not say that passing gas lowers blood pressure. Intestinal gas often indicates that foods have fermented in the colon instead of being completely digested.

Air, food, and liquids are moved through your digestive system by the contraction of muscles in the walls of your intestines.

There are two other ways in which gas can escape your intestine than release through the anus.

First, it can be absorbed across the lining of the intestine into your blood (perhaps aiding the effect the researchers above observed). The gas then travels in the blood and ultimately, if in excess, is excreted on your breath.

Second, gas can be removed and used by certain types of bacteria within the intestine. In fact, most of the gas that is formed by bacteria in the intestines is removed by other bacteria in the intestines.

Often, gas is eliminated at night as you sleep.

Three factors are often cited as causes for flatulence: swallowing air; improperly digested sugars and starches; and an imbalance of bacteria and fungus in the small intestine.

Small amounts of air are frequently swallowed. Eating too quickly and scanty chewing allow greater quantities of air to enter your digestive tract. Swallowed air is sometimes cited as a source of flatulence, however, it is rarely the cause. Yet, thorough chewing of food can go a long way toward relieving numerous digestive maladies.

Bacteria produce H2S and/or methane (both containing sulphur) when they encounter sugars, starch, and cellulose that have not been digested during passage through your small intestine.

Sorbitol, fructose, and lactose are common sugars that are poorly digested and poorly absorbed.

Sorbitol is a sweetener commonly used in low calorie foods. Fructose is used to sweeten all types of sauces, candies, and drinks – it is found almost everywhere. These sugars have been implicated in a variety of other maladies, so they should be consumed only occasionally, if at all.

Lactose is the sugar in milk. Absence (often a genetic trait) of an enzyme called lactase in the intestinal lining causes digestive trouble. Lactase breaks down lactose so that it can be absorbed through the intestine walls into the blood stream. Enzymes similar to intestinal lactase are added to milk products to break down lactose prior to consumption so it can be absorbed normally. The protein, casein, is a more common factor in milk allergy, causing similar symptoms.

Some people find that switching to yogurt, in which lactose has been broken down partially by bacteria, produces less gas than milk. Goat’s milk is more digestible than cow’s milk and is often tolerated better by people allergic to cow’s milk.

Starches are polysaccharides produced by plants. They are composed of long chains of sugars. Common sources of significant amounts of starch include wheat, oats, potatoes, corn, and rice. Rice is the most easily digested starch. Little undigested rice starch reaches your colon and the colonic bacteria. Therefore, eating rice produces little gas. Starches in wheat, oats, potatoes, and, to a lesser extent, corn, may reach the colon and the bacteria in substantial amounts. These starches can result in the production of appreciable amounts of gas.

The first line of defense against this accumulation of gas is chewing. Forty percent of starch digestion happens when your food is thoroughly mixed with saliva. Receptors in your mouth cue key enzymes to be ready to complete the digestion of these starches in your small intestine. Pancreatic enzymes, when not overwhelmed by poorly masticated foodstuff, break down sugars and starches so that they can be used as energy by your body.

Certain fruits and vegetables contain harder to digest starches that reach the colon and result in the formation of gas. These include beans, dried beans, cabbage, Brussels sprouts, onions, carrots, bananas, and dried fruits. Reducing the intake of these vegetables and fruits, as well as foods made from whole grains, may reduce gas and flatulence. However, the list of gas-producing foods is rather long, and it may be difficult to eliminate them all without severely restricting your diet. Additionally, many of these foods offer significant health benefits.

As above, chewing each bite a couple of dozen times can make a big difference.

Pre-soaking beans and slow cooking with digestion enhancing herbs (e.g., cumin, ginger, coriander) can make a difference.

Supplemental enzymes may be helpful in the short run as well. One such treatment for excessive gas is alpha-D-galactosidase, an enzyme produced by a mold. This enzyme is able to break down some of the difficult-to-digest starches in vegetables so that they may be absorbed. This prevents them from reaching the colonic bacteria and causing unnecessary production of gas. Available as Beano, it is consumed as either a liquid or tablet with meals. Beano has been shown to be effective in decreasing the incidence of intestinal gas.

Often, continuing to eat ‘offending’ foods frequently (in smaller quantities) will acclimate the body to them, allowing it to produce the proper enzymes for their digestion. It is particularly important to eat raw, fresh fruits and vegetables to replenish these enzymes.

Most vegetables and fruits contain cellulose, another type of polysaccharide that is not digested at all as it passes through the small intestine. However, unlike sugars and other starches, cellulose is used only very slowly by colonic bacteria. Therefore, the production of gas after the consumption of fruits and vegetables usually is not great unless the fruits and vegetables also contain sugars or polysaccharides other than cellulose.

We know cellulose better as fiber. Fiber slows the digestion of sugars and starches, allowing more even blood sugar. Further, fiber absorbs certain toxins in your intestines. It pushes out debris from your intestines, leading to more regular cleaning of potential trouble makers from your system. The whole mess is then evacuated with the feces. Clearing your digestive system daily like this also leads to relief from the embarrassment of flatulence.

Under normal conditions, bacteria that produce gas are limited to the colon. In some medical conditions, however, these bacteria spread backward into the small intestine. When this bacterial spread occurs, food reaches the bacteria before it can be fully digested and absorbed by the small intestine. The foreign bacteria in the small intestine have a lot of undigested food from which to form gas.

Fermented foods (e.g., miso, sauerkraut, yogurt, kimchi) are enzyme rich foods, alive with micro-organisms. Fermentation allows bacteria, yeasts and molds to "predigest" or break down carbohydrates, fats, and proteins to create "Probiotics." These friendly bacteria keep your immune system strong and support overall digestive health. They:

● aid in digestion.
● promote healthy flora in your digestive tract.
● produce beneficial enzymes.
● offer you better nutrition.
● allow your body to absorb vitamins (in particular C, and B12), minerals, nutritional value and omega 3s more effectively from foods.
● regulate the level of acidity in the digestive tract
● act as anti-oxidants.
● contain the same isothiocyanates found in cruciferous vegetables and therefore fight and prevent cancer.

Flatulence causes an annoying and embarrassing situation. The gas itself is useful in the circulatory system, as long as it gets there and can be used properly. Taking steps to prevent flatulence can also improve your overall health, including your blood pressure.


Resources:
http://www.sciencemag.org/cgi/content/abstract/322/5901/587
http://www.sciencemag.org/cgi/data/322/5901/587/DC1/1
http://news.yahoo.com/s/livescience/20081023/sc_livescience/thestinkinfartscontrolsbloodpressure
http://www.lef.org/abstracts/codex/l-cysteine_abstracts.htm
http://www.medicinenet.com/intestinal_gas_belching_bloating_flatulence/page2.htm#tocc

17 October, 2008

Moderate Alcohol Consumption Shrinks Brain

We have been told that moderate use of alcohol is good for the heart. However, reports from the Framingham Study show that moderate to heavy alcohol use is associated with damage to brain tissue. Such damage to the brain may lead to higher risk of stroke or dementia.

The Framingham Study began in 1948 to follow the residents of Framingham, Massachusetts and their offspring. The study is now following a third generation of participants. The goal of the study is to follow people over a long period of time, documenting their state of cardiovascular disease.

At the beginning of the study, subjects have no evidence of heart disease. The subjects are put through a series of tests every two years. Over time, medical records are analyzed to determine risk factors for cardiovascular disease. Much of the information published about risk factors for heart disease and stroke comes from this study.

The American Academy of Neurology presented evidence in 2007 from Wellesley College, Massachusetts. Carol Ann Paul M.S. and her associates reported that even moderate amounts of alcohol are associated with brain atrophy and possibly an increased risk of dementia or stroke.

Researchers performed MRI scans on 1,839 people aged 34 to 88 to compare the volume of brain tissue to their cranial size. Subjects were classified as non-drinkers, former drinkers, low drinkers (1 to 7 drinks per week), moderate drinkers (8 to 14 drinks per week), or high drinkers (more than 14 drinks per week). Brain shrinkage numbers increased by .25 percent as amount and frequency of drinking increased. People who consumed more than 14 drinks per week had brains which averaged 1.6 percent smaller than those who did not drink alcohol. For women, especially those in their 70's, the change was more dramatic than for men. Researchers speculated that the differences may be associated with the smaller body mass of women. In addition, those who had a longer history of heavy alcohol consumption also had more brain atrophy. The team noted that men were more likely to become heavy drinkers than women.

The same group reported again in 2008 in the Journal of the American Medical Association: "The public health effect of this study gives a clear message about the possible dangers of drinking alcohol," the authors write. "... This study suggests that, unlike the associations with cardiovascular disease, alcohol consumption does not have any protective effect on brain volume.” They suggest further, longer term studies to determine the full impact of these findings.

In general, brain volume decreases with age at an estimated rate of 1.9 percent every ten years. At the same time white matter lesions replace grey matter. Lower brain mass and white lesions are associated with problems in movement, thinking, learning, and memory.

A 2006 study from the Erasmus Medical Center in Rotterdam observed that people who developed dementia decreased in brain volume between 5 and 17 percent during the eight year study. Those who were diagnosed with Alzheimer’s had a decrease up to 40 percent. People with atrophy in parts of the brain known as the amygdala and hippocampus had the highest risk of developing dementia or Alzheimer's disease.

The accelerated loss of grey matter under the influence of alcohol is worth considering before you down that second (or third) serving of spirits.

Resources

JAMA and Archives Journals (2008, October 14). Drinking Alcohol Associated With Smaller Brain Volume. ScienceDaily. Retrieved October 16, 2008, from http://www.sciencedaily.com/releases/2008/10/081013171421.htm

Johns Hopkins University Bloomberg School Of Public Health (2003, December 5). Moderate Alcohol Consumption Linked To Brain Shrinkage. ScienceDaily. Retrieved October 16, 2008, from http://www.sciencedaily.com/releases/2003/12/031205052952.htm

American Academy of Neurology (2007, May 3). Drinking Heavy Amounts Of Alcohol Shrinks Your Brain. ScienceDaily. Retrieved October 16, 2008, from http://www.sciencedaily.com/releases/2007/05/070502172317.htm

http://www.abstracts2view.com/aan2007boston/html/P05.030.html

http://www.redorbit.com/news/health/347670/reduced_brain_volume_may_predict_dementia/index.html

08 October, 2008

Bad Eating Habits Produce Inflammation and Changes in Behavior

Overeating is a self perpetuating habit which has devastating health effects. The habit sets off a series of events which short circuit the normal signals the body gives to regulate eating habits. All this leads to wide spread inflammation, contributing to chronic diseases like arthritis, diabetes, heart disease, and cancer. Apparently food choices make changes, not only in your health, but in your behavior as well. Overweight people approach food differently.

A new study published in the October 3rd issue of the journal Cell found that overeating causes changes in the brain.

The hypothalamus is a cone shaped gland, about the size of an almond, attached to the pituitary gland and lying near the brain stem. It is the mechanism which helps the body maintain homeostasis – the tendency toward a stable, constant state of equilibrium. The hypothalamus regulates body temperature, hunger, thirst, fatigue, anger, sexual desire, blood pressure, water balance, and circadian cycles. The nervous system and endocrine system communicate through the hypothalamus.

A protein called IKKbeta/NK-kappaB is normally present in the hypothalamus in large quantities. However, it is not generally released into body tissues. This substance is used by macrophages and leukocytes, triggering inflammation throughout the body. It is as if the immune system tries to attack and destroy an invader which is not there. Researchers speculate it may have been an important element in a the body's first line of defense against pathogenic invaders at some time in the distant past.

In our day, it is activated by a different mechanism. A high fat diet releases IKKbeta/NK-kappaB from the hypothalamus. When they fed mice a high-fat diet, activity in the pathway which releases this protein doubled. It increased even more in mice genetically prone to obesity. Release of this protein results in resistance to insulin and leptin. Resistance to these hormones hold a key to the development of diabetes and heart disease. These researchers feel they have discovered a ‘master switch’ for the diseases caused by overeating. Inflammation and obesity are intertwined.

Insulin is the hormone produced by the pancreas which stimulates the cells to take up glucose and stops use of fat as an energy source.

Leptin plays a key role in regulation of appetite, metabolism, and reproductive function. It is a hormone that normally helps regulate appetite, and insulin, and helps convert food into energy. Produced by fat cells, it signals the body to shut off the appetite and encourages physical activity to burn off energy. Leptin also regulates insulin. At night, when the body is at rest, leptin is decreased by the presence of melatonin.

Oddly, in obese people, large quantities of leptin are found circulating in the blood. It is now thought that IKKbeta/NK-kappaB produces leptin resistance. In the study, when the protein was active, the mouse’s body ignored signals from leptin. Stimulating its release made the mice eat more, while suppressing it made them eat less.

"Knocking out" the gene controlling this pathway through genetic engineering kept mice eating normally and prevented obesity, even though a high fat diet was available to them. Such genetic engineering cannot be done in people.

The ultimate goal: to identify a selective and effective suppressor of the pathway to target related neurons. The researchers believe a drug, or even gene therapy, might work.

With gene therapy, a virus or other so-called vector is used to carry corrective DNA into the body, but the approach is still highly experimental.

Other scientists are leery of these conclusions. The complexity of the controls governing human metabolism, appetite and the laying down of fat has become clear over recent years. If we have some drugs that target this pathway, they may well interfere with some other part of the immune system.

Not all fats are guilty of stimulating the pathway described above. We suspect that the mice studied were fed a diet similar to the Standard American Diet (SAD). This diet is typically high in saturated fats and simple carbohydrates.

Another study out of UC Irvine, reported in the October 8 issue of Cell Metabolism, demonstrated a different mechanism affecting hunger. An unsaturated fat, oleic acid – found in olive oil, avocados and nuts – triggers a compound, called oleoylethanolamide (OEA), in the small intestine which curbs hunger pangs. Oleic acid, transforms into OEA by the action of cells in the upper region of the small intestine. After several minutes, OEA activates nerve endings which carry a hunger-curbing message to the brain. The signals activate a brain circuit (in the hypothalamus) that increases feelings of fullness. The process can take up to twenty minutes. Previous studies found that increasing OEA levels can reduce appetite, produce weight loss and lower blood cholesterol and triglyceride levels.

Your choice of foods, beyond fat content, can affect the inflammation level in your body. Regular consumption of anti inflammatory foods may lead to reduction of inflammation on your body. Following is a list of foods which have been found to have anti inflammatory action:

Vegetables

Bell Peppers
Bok Choy
Broccoli
Broccoli Sprouts
Brussels Sprouts
Cabbage
Cauliflower
Chard
Collards
Fennel Bulb
Garlic
Green Beans
Green Onions/Spring Onions
Kale
Leeks
Olives
Spinach
Sweet potatoes
Turnip Greens

Fruits

Acerola (West Indian) Cherries
Apples
Avocados
Black Currants
Blueberries
Fresh Pineapple
Guavas
Kiwifruit
Kumquats
Lemons
Limes
Mulberries
Oranges
Papaya
Raspberries
Rhubarb
Strawberries
Tomatoes

Herbs and Spices

Basil
Cayenne Peppers/Chilli Peppers
Cinnamon
Cloves
Cocoa (at least 70% cocoa chocolate)
Licorice
Mint
Oregano
Parsley
Rosemary
Thyme
Turmeric

Fish

Cod
Halibut
Herring
Oysters
Rainbow Trout
Salmon
Sardines
Snapper Fish
Striped Bass
Tuna
Whitefish

Nuts and Seeds

Almonds
Flaxseed/Linseed
Hazelnuts
Sunflower Seeds
Walnuts

Oils

Avocado Oil
Extra Virgin Olive Oil

Drinks

Green Tea

Did you ever notice the way people approach buffet food bars? A study, reported in the June issue of the journal Obesity, analyzed the habits of people at all-you-can-eat Chinese restaurants.

Trained observers recorded the height, weight, sex, age, and behavior of 213 patrons at 11 restaurants. Various seating, serving, and eating behaviors were then compared across BMI levels. Dramatic differences were observed depending on the person’s body mass index (BMI).

Obese people found ways to make the food more convenient to eat. Thus they tended to eat in excess. Rather than surveying the food bar to decide what they want, they were more than three times as likely to seize a plate and start filling it. They used larger plates. They chose seats an average of 16 feet closer to the food bar. Facing the food bar was a preferred position.

Those with lower BMI were twice as likely to sit in a booth, rather than at a table. They put a napkin in their lap and chose to eat with chopsticks rather than a fork more frequently. Each bite was chewed longer by normal weight people compared to those who had higher BMI.

Appetite is a very complex subject. However, we do know that poor food choices and attitudes and habits surrounding food both contribute to and perpetuate overeating and its resulting chronic illnesses.

References:

http://news.yahoo.com/s/nm/20081002/sc_nm/us_obesity_brain

http://news.bbc.co.uk/2/hi/health/7649261.stm

http://www.nature.com/oby/journal/v16/n8/abs/oby2008286a.html

http://www.cell.com/content/article/abstract?uid=PIIS0092867408010088

http://www.sciencedaily.com/releases/2008/06/080619203254.htm

http://www.sciencedaily.com/articles/h/hypothalamus.htm

http://www.becomehealthynow.com/article/bodynervousadvanced/956/


Cell Press (2008, October 3). Brain Pathway Responsible For Obesity Found: Too Many Calories Send Brain Off Kilter. ScienceDaily. Retrieved October 6, 2008, from http://www.sciencedaily.com/releases/2008/10/081002171908.htm

University of California - Irvine (2008, October 7). How Fatty Foods Curb Hunger. ScienceDaily. Retrieved October 8, 2008, from
http://www.sciencedaily.com/releases/2008/10/081007123647.htm

http://www.physorg.com/news142597893.html

http://www.metabolismadvice.com/anti_inflammatory_food/

http://www.usatoday.com/news/health/weightloss/2008-10-01-chinese-buffets_N.htm?csp=34

01 October, 2008

Choosing the Best Apple Juice for your health

Fruits and vegetables are a good source of antioxidants. Antioxidants are compounds that neutralize free radicals -- molecules that can damage body cells and contribute to disease. With an emphasis on eating healthier, people are trying to find ways to consume the recommended five to seven servings of fruits and vegetables each day. Many are overwhelmed at the concept of putting that many items on their plates throughout the day (my kiddos, however, would cite me for child abuse if they were limited to five servings). Spurred by certain advertising, many people now consume fruit and/or vegetable juices to augment their antioxidant intake.

As always, read labels before you choose a juice. Many bottled juices contain little to no real juice -- only sweeteners (and increasingly they are sweetened with toxic artificial sweeteners), flavor enhancers, and preservatives. “Juice drinks” may contain ten to twenty-seven percent juice, plus high fructose corn sweeteners (and the aforementioned artificial sweeteners). Look for 100% juice, but don't stop there.

In a head-to-head comparison of apple juices, Polish researchers found that pulpy, non-clarified juice carried a greater antioxidant punch than clear juice. Clear juices are processed to remove any solids in the juice. This makes a ‘prettier’ juice and increases its shelf life, but it turns out that those solids are the storehouse for many nutrients. Juice with pulp contained four times as many polyphenols as clear juice. Polyphenols have been studied for their effects which may reduce cardiovascular disease and cancer.

“Cloudy apple juices contain much more antioxidant than clear,” concludes Dr. Jan Oszmianski, the study’s lead author and a researcher at the Agricultural University of Wroclaw. Her study was published in Journal of the Science of Food and Agriculture. In the end, however, your best bet for getting the most nutrition is to eat the whole apple. Look for the ‘older’ varieties. The newer varieties tend to have lower nutrient content. they are bred for eye appeal and for shelf life, not for nutrition. ‘Cider’ apples ranked highest in nutrients of all the apples tested (Journal of the Science of Food and Agriculture).

While we are on the subject of apples:

In medieval times, a saying was coined: “Ate an apfel avore gwain to bed Makes the doctor beg his bread.” The saying has come down to us as: “An apple a day keeps the doctor away.” Modern research indicates that there may be some truth in the old saying. Apples also have significant amounts of a wide array of important phytonutrients that research has found to have extremely important health benefits.

* They are an excellent source of fiber, which keeps the digestive tract working properly. Fiber absorbs a number of toxins from the body.

* Quercetin, which is available in apples, inhibits, reduces, or prevents the growth of human prostate cancer cells by blocking activity of androgen hormones (Carcinogenesis, 2001, 22: 409-414). Increased consumption of quercetin is also associated with a reduced risk of lung cancer (Journal of the National Cancer Institute, 2000, 92: 154-160).

* Phytonutrients in apples inhibit the growth of colon cancer and liver cancer cells in vitro. Beneficial phytonutrients are most strongly concentrated in the apple skin, but the apple flesh also contains significant levels of phytonutrients (Nature, 2000, 405: 903-904).

* In a long term study in Finland, lung cancer was 46 percent lower among those whose diets contained the highest amount of flavonoids, particularly from apples. Of the major dietary flavonoid sources, apples showed the greatest inverse association with lung cancer incidence. (American Journal of Epidemiology, 1997, 146: 223-230).

* British analysis of dietary habits indicates a strong positive association between positive lung function and the number of apples eaten each week (Thorax, 2000, 55:102-108).

* Apples and apple juice may help to slow the oxidation process that leads to the build-up of plaque (LDL or ‘bad’ cholesterol) that leads to heart disease (Journal of Medicinal Food, 2000, 3: 159-165; Life Sciences, 1999, 64: 1913-1920).

* The Finnish Study also concluded that high consumption of flavonoids from apples and onions was directly associated with the lowest death risk from coronary factors (British Medical Journal, 1996, 312: 478-481) and the lowest risk of thrombotic stroke (European Journal of Clinical Nutrition, 2000, 54: 415-417).

If you would prefer juices, fresh whole juices deliver both abundant nutrients and a full spectrum of helpful enzymes to allow your body to digest all foods more effectively.

Sources:

http://www.wroclaw.com/university/index.html
http://www3.interscience.wiley.com/cgi-bin/abstract/113494176/ABSTRACT
http://www.carcinogenesis.com/
http://jnci.oxfordjournals.org/
http://www.nature.com/nature/index.html
http://aje.oxfordjournals.org/
http://thorax.bmj.com/
http://www.liebertpub.com/publication.aspx?pub_id=38
http://www.bmj.com/
http://www.nature.com/ejcn/index.html

29 September, 2008

Effect of Caffeine on Stress Levels and Teamwork

“Taking a coffee break at work may actually sabotage employees’ ability to do their jobs and undermine teamwork instead of boosting it, suggests new research.” So begins an article in New Scientist. We thought coffee breaks reduce stress. Have you noticed however, that after drinking coffee, stressful personal interactions do actually become more tense? Men tend to speak much louder, escalating into yelling or shouting.

A pair of scientists from Bristol University were inspired by a report of an attendee at one of their stress workshops.

The man traveled to the U.S. with his workmates. They found coffee more available in the U.S. than it is in the U.K. The men in his entourage took advantage of the readily available source of their favorite drug. He related that “within days their stress levels had escalated and they believe the extra caffeine had disrupted their working relationships, and impaired their working ability.”

Back in the ‘lab,’ these two scientists set up a scenario to test the effects of java on people’s stress levels and working relationships. They gave subjects a beverage containing 200 milligrams of caffeine (about 2 cups of espresso) or a caffeine-free cup.

The most pronounced effects seemed to be on the men in the study. Men had higher heart rates and used less adaptive coping strategies under the influence of caffeine. They had more difficulty during a public speaking task after drinking coffee. However, their performance in mathematics was not affected by the beverage. Surprisingly, levels of alertness were similar whether or not participants drank caffeinated beverages.

Given a group ‘desert survival task,’ taking a coffee break reduced indicators of stress, but reduced men’s ability to perform as a team. The effect was more pronounced in men than their female counterparts. Jim Lane of Duke University, theorizes that men may be more threatened by stressful situations. Stress is amplified by caffeine.

A separate report from BBC News explains that it is indeed possible to get too much coffee: “Indulging in a few mugs too many could result in symptoms such as restlessness, nervousness, excitement, insomnia, nausea, vomiting and a flushed face. The symptoms of a serious overdose include delirium and seizures.”

Caffeine overdose can be fatal, in the short term, if not in the long run. “Death from an extreme overdose would tend to be due to ventricular fibrillation -- an uncoordinated contraction of heart muscles, which could stop blood pumping.” the BBC article reports. Toxicity reactions may occur with consumption of as few as seven cups of coffee per day, the article explains. Individual sensitivity may vary, however. Some people may exhibit symptoms from less java, while others may be able tolerate a bit more.

Caffeine is an addictive drug. Those who consume at least 600 to 750 milligrams of caffeine per day will find it difficult to go without their daily fix.

How much caffeine is in that cup? The BBC reports: “The highest natural caffeine content is found in filter coffee, a mug of which contains about 120 mg of caffeine. Instant coffee contains roughly 75 mg and espresso 107 mg.”

They do not explore the effect of long term use of excessive amounts of caffeine consumption. Some studies suggest a link between habitually large consumption of coffee and fibromyalgia.

Caffeine is by far the most commonly consumed psychoactive substance. Perhaps, when it is time to take a break, it would be better to take a walk, drink ordinary H2O, and take several deep breaths than to hit Starbucks.

References:

newscientist
bbc

26 September, 2008

Natural Relief for Laryngitis

Laryngitis leaves a person speechless. At best, the person speaks in a raspy tone or in a whisper. Severe cases lead to a complete loss of the voice. It is inconvenient, especially if your occupation involves a great deal of vocal communication. Acute laryngitis lasts just a few days, but chronic cases can last weeks or even longer. Sometimes it is painful.

The larynx is located in the throat. It is commonly known as vocal chords or vocal folds. It becomes inflamed (the ‘itis’ part of laryngitis) for a number of reasons. A virus, as in a cold, is the most common cause. Bacteria and fungal infections can also cause hoarseness. The coughing which comes with respiratory illness may lead to laryngitis. Over use or abuse of the vocal chords through excessive shouting or incorrect singing habits stress the voice, causing inflammation. Smokers may find themselves with a case of laryngitis. A heavy bout of alcohol intake irritates the throat as well. The throat may erode due to acid reflux. Occasionally, the vocal chords may be disturbed by the presence of a tumor, leading to loss of vocal power.

We cannot claim to cure or treat laryngitis. Natural healing does not necessarily offer specialized recommendations. Instead, illness or disease is seen as an indication that the body is over loaded with issues which cause stress. Issues range from improper care for your body to toxic pollutants.

In our hectic lives, we often neglect the proper care and feeding of our bodies. Insufficient rest, junk food (and drinks), and exposure to environmental toxins take their toll.

At the first sign of a sickness, one needs to realize that the body has been under more stress than it can handle. Too often, we want to take a cup of tea or some pills and continue doing what we have been doing all along. Think again.

Many natural healers recommend beginning intervention for particular ailments with the simplest remedies.

So, let us begin with a common recommendation: get rest and drink plenty of fluids.

Sleep is underrated as a healing modality. True, many ills need a bit more than extra sleep for their resolution, but resting in bed (or on the sofa during the daytime) allows the body to pour its energy more effectively into the immune system.

In addition, while you sleep, in the dark of night, melatonin is produced. Melatonin is important in regulating the body’s daily (circadian) rhythm. It is a powerful antioxidant, which can cross cell membranes and the blood brain barrier. Even the products of melatonin’s attack on free radicals have antioxidant activity. Longevity is one of the side effects of melatonin’s action in the body as it seems to generate a powerful response from the immune system. It may assist in fighting viral and bacterial infections, including those which may be implicated in laryngitis.

So, get plenty of rest, especially in a dark room at night. If you need to get up, do not turn on a light. And when you wake up, be sure to drink plenty of water.

Water is essential to life. The body is at least seventy percent water. The body counts on blood and lymph fluids as transportation systems. They carry nutrients and immune system components to where they are needed and cart off waste products. Too many people stumble through their day to day lives depriving their bodies of necessary fluids or consuming substances which decrease the available fluids. So, it is essential that one increase fluid intake during times of stress.

Certainly, the first choice of fluids is good quality water. Much has been written about pure water so we need not cover that topic here. Suffice to say that if you drink contaminated water, it will be more difficult for the body to focus on cleaning up the vocal chords.

Eliminate dairy products. While that dish of ice cream may sound appealing when your throat is hot and sore, its effect will be extremely short lived. Milk products tend to increase mucus production in the body, which tends to muck things up. In the end, mucus accumulation makes it more difficult for the immune system to send in the troops.

Other helpful liquids are available which can assist in clearing the mess which has led to the laryngitis.

Honey has been shown to be as effective as patent cough syrup. It is astringent, clearing away inflammation and some of its causes. Raw honey has enough sugar in it to give that little boost of energy, but many of the enzymes to help the body effectively use that sugar. The little bit of nutrition in honey also helps in healing.

Add freshly squeezed lemon juice (or raw apple cider vinegar) in equal parts with the honey. This can provide vitamin C and some of the electrolytes which help to bring the acid/alkaline balance back to unhealthy tissues.

Squeeze the juice from half a lemon, mix it with a tablespoon or two of honey. Add this mixture to a cup of water. It does not matter if the water is warm or cool. Now, stir in one tenth teaspoon of cayenne pepper. Yes, you read that right – cayenne pepper. The cayenne helps to break up mucus accumulation in and around the inflamed tissue.

A similar recipe, substituting grade B maple syrup for the honey constitutes the Master Cleanse. During the cleanse, drink ten to twelve cups of this lemonade throughout the day. Generally the Master Cleanse is presented as a form of fasting. You probably don’t feel much like eating when your throat is so sore and swollen.

If the concept of hot pepper intimidates you, try mixing honey and lemon in sage tea. Steep a tablespoon of dried sage leaves in three cups of boiling water. Do not boil the sage leaves, just pour the boiling water over the leaves and cover for fifteen minutes. Strain and add lemon and honey as above.

Another remedy recommended by the old herbalists is garlic syrup. Peel and chop the cloves of several garlic heads and place them in a jar. Cover with equal parts apple cider vinegar and distilled water. Shake well and allow to sit for four hours. Strain and add an equal amount of honey. Shake together. Cap. Store in the refrigerator. Take a teaspoon to a tablespoon every six to eight hours.

We cannot leave this subject without mentioning Grandma’s favorite remedy for what ails you: Chicken soup. Any soup, for that matter, which is made with lots of herbs and vegetables provides easily digestible nutrition. Our fore-mothers knew, perhaps intuitively, that herbs are for much more that taste. Many of them have antibiotic properties and can be a strong ally in repairing the damage we do to our bodies from day to day.

When you have laryngitis, realize that your body is telling you that you have not given it the care it deserves. Slow down, and get extra rest. You will find that you don’t have much appetite, so don’t be afraid to cut back on your food intake (especially those junk foods that we are all so fond of). Drink plenty of fluids. Honey, lemon, sage, and garlic are primary tools for getting back in communication with your world.

17 September, 2008

Vaccine Refusal

A friend posted this on her blog. The data is a couple years old, but it is the most comprehensive treatment of the subject I have seen in one place.

Please note: This is NOT an exemption form. This document is designed to facilitate the discussion between you and those you choose to discuss your decision to refuse vaccines. Many states have prescribed forms which they use for exemption purposed. Check the exemption page on this web site for a link to individual state laws. [Note: I found a more current site for vaccine exemption forms, so the link above has been updated.

Also, here is a link to a current, detailed, general exemption letter.

REFUSAL OF RECOMMENDED VACCINES

Patient Name_______________________________ Birthdate_______________

As the parent/guardian of __________________________, I have investigated the risks and benefits of the following vaccines and diseases. I am aware that there are documented cases of people contracting diseases for which they are clinically fully immunized and that the manufacturers of the vaccines do not guarantee 100% efficacy. I am also aware that VAERS (Vaccine Adverse Events Reporting System) documented cases of over 54,000 adverse reactions from vaccines in a 20-month period. The Vaccine Injury Compensation Program (The Vaccine Court) received 366 new petitions for compensation between 1/5/04 and 3/30/04. The National Vaccine Injury Fund, created in 1986 to compensate families of vaccine-damaged children, had paid out over 1.4 billion dollars in compensation 1986 to 10/21/04.

POLIO: I have been informed of the risk of my child developing paralytic disease and meningitis associated with poliomyelitis. I understand that even under epidemic conditions, natural polio produces no symptoms in over 90% of those exposed to it.(1) I understand that there have been no cases of wild polio in the US in the last 20 years and that those cases which have been documented have been caused by the vaccine.(2)
I understand the following side effects for the vaccine are possible:
Killed virus polio: temperature of *102° in up to 38%, sleepiness, fussiness, crying, decreased appetite, vomiting, Guillain-Barré Syndrome and allergic reaction in those allergic to neomycin, polymyxin B and streptomycin. Precautions include those who have had a previous negative reaction, pregnant women, and possibly those with HIV/AIDS or otherwise compromised immune systems.

Live virus polio: Reactions include contraction of polio by those who have received the virus and by those who have come into contact with body fluids and wastes of the immunized person. Paralytic symptoms may follow contraction of polio. Live virus is reportedly shed for up to 8 weeks after the inoculation. Guillain-Barré Syndrome has also been noted. Not recommended for use in households where someone has a compromised immune system, for pregnant women, or where a previous reaction has been reported.(3)

Killed virus Ipol® is grown on monkey kidney cells, contains formaldehyde, and triple antibiotics. Poliovax® is grown on cells from an aborted baby, contains formaldehyde, cow serum and triple antibiotic solution.(4) The monkey kidney cells used in the original killed polio vaccine contains SIV-40 and has been found in tumor cells of children whose parent’s were vaccinated against polio using the contaminated virus.(5) The live vaccine is grown on monkey kidney cells, antibiotics and calf serum.

HEMOPHILUS INFLUENZAE B: I have been informed of the risk of my child developing meningitis (although this vaccine will not protect the child from meningitis from all other forms such as pneumococcus, and meningococcus, viruses, and fungi), pneumonia, and infections of the blood, joints, bone, and soft tissue associated with Hemophilus Influenzae B. I understand that this disease is most likely in children up to 15 months of age and is fatal in 3-6% of children who contract it. Incidence of this disease today is low and the vaccine has not proven to be highly effective in 41% of cases, according to some studies.(6) Treatment is available.

The vaccine is often combined with the DPT which has the highest reaction rate of any vaccine available today. Reactions include: contracting HIB, localized pain, erythema and induration, fever >100.6°, irritability, lethargy, anorexia, rhinorrhea, diarrhea, vomiting, cough, when administered alone. Reactions occurred in up to 30% of patients. When administered in conjunction with the DPT, reactions include local tenderness erythema and induration, fever >100.8°, irritability, drowsiness, anorexia, diarrhea, vomiting, persistent crying, seizures, urticaria, hives, renal failure, Guillain-Barré Syndrome and death. Reactions occurred in up to 77.9% of patients.(7)
The vaccine contains yeast, thimerosal (mercury derivative), and diphtheria toxoid when given alone.(8)

PERTUSSIS: I have been informed of the risk of my child developing whooping cough, pneumonia, convulsions, inflammation of the brain, and death associated with pertussis. I understand the disease is rarely fatal, with a 99.8% recovery rate. It is most serious and life-threatening in children under 6 months old, but there are adequate methods of treatment available.(9)

The vaccine is most often given in conjunction with diphtheria and tetanus as the DPT or as the DaPT.

Pertussis vaccine may cause: fevers >106, pain swelling, diarrhea, projectile vomiting, excessive sleepiness, high–pitched screaming, inconsolable crying bouts, seizures, convulsions, collapse, shock, breathing problems, brain damage and SIDS. One in 600 suffer a severe reaction in one study (10) and 1 in 875 suffered shock-collapse and convulsions.(11) Those in the 2nd study were only tracked for the first 48 hours following immunization. A more recent study indicates that 1 in 100 react with convulsions, collapse, or high-pitched screaming and 1 in 3 of those cases sustained permanent brain damage.(12) In a study of 103 children who died of SIDS, 70% died within 3 weeks of the DPT vaccine and 37% of those died within the first week.(13)

The DaPT is recommended as a safer option for vaccination. Side effects of the DaPT were only tracked for 72 hours and included: tenderness, erythema, induration, fever >102.2°, drowsiness, fretfulness, vomiting, upper respiratory infection, diarrhea, rash, febrile seizures, persistent or unusual crying, lethargy, hypronic-hyporesponsive episode, urticaria, anaphylactic shock, convulsions, encephalopathy, mono- and polyneuropathies and death.(14) Not recommended for children under 15 months or for those who have not had 3 injections of the DPT.

Either form of the vaccine contains thimerosal (mercury derivative), formaldehyde, and aluminum phosphate.(15)

DIPHTHERIA: I have been informed of the risk of my child developing paralysis, heart failure, or respiratory failure associated with diphtheria. I have also been informed that there have only been 5 cases reported annually since 1980.(16) I am also aware that diphtheria is rarely fatal and treated with antibiotics and bed rest. (17)

The Diphtheria component is most often given within the DPT or DaPT and includes the same side effects and reactions as those listed for pertussis.

TETANUS: I have been informed of the risk of my child developing fatal neuromuscular disease related to tetanus. I understand that the incidence of tetanus is low, and there is an antitoxin, should we decline the immunization. I understand that contracting tetanus does not provide life-long immunity, and neither does the vaccine. I understand that to prevent more severe reactions from the vaccine, the tetanus component has been so significantly “diluted” that it is clinically ineffective.(18) I understand that the death rate for properly treated cases of tetanus may be as high as 20%.(19)

Side effects of the tetanus vaccine alone include: high fever, pain, recurrent abscess formation, inner ear nerve damage, demyelinating neuropathy, anaphylactic shock and loss of consciousness.(20)

Tetanus given in the DPT or DaPT shot include the same side effects and reactions as those listed for pertussis.

RUBEOLA (MEASLES): I have been informed of the risk of my child developing pneumonia, encephalitis (inflammation of the brain), degenerative disease of the nervous system with convulsions (subacute sclerosing panencephalitis) related to rubeola. I understand the death rate for measles is .03 in 100,000.(21) I understand that since 1984, over 55% of documented, confirmed cases of measles have been in fully immunized persons.(22)

I understand that the greatest risk of the measles vaccine may be to push the incidence of this disease into the late teens and adulthood where it is more likely to be fatal or cause more adverse and long-term effects.(23)

The measles vaccine is a live vaccine, and carries the risk that it will cause the patient to contract measles. Other adverse reactions include: stinging or burning at the injection site, anaphylaxis, fever up to one month following injection, rash, cough, rhinitis, erythema multiforme, lymphadenopathy, urticaria, diarrhea, febrile convulsions, seizures, thrombocytopenia, purpura, vasculitis, optic neuritis, retrobulbar neuritis, papillitis, retinitis, encephalitis and encephalopathy, ocular palsies, Guillain-Barré Syndrome, ataxia, and subacute sclerosing panencephalitis.(24)
Measles vaccine is most often given as a part of the MMR which includes the following side effects: burning or stinging at injection site, malaise, sore throat, cough, rhinitis, headache, dizziness, fever, rash, nausea, vomiting, diarrhea, erythema, induration, tenderness, lymphadenopathy, parotitius, orchitis, nerve deafness, thrombocytopenia, purpura, allergic reactions, urticaria, polyneuritis, arthralgia, arthritis, anaphylaxis, vasculitis, otitis media, conjunctivitis, febrile convulsions, seizures, syncope, erythema multiforme, optic neuritis, retrobulbar neuritis, papillitis, retinitis, encephalitis and encephalopathy, ocular palsies, Guillain-Barré Syndrome, ataxia, subacute sclerosing panencephalitis,(25) and a recent study from Europe indicates that there may be a link between the MMR (measles/mumps/rubella) vaccine and autism and irritable bowel syndrome.(26)

Measles vaccine contains chick embryo cells, neomycin, sorbitol and hydrolyzed gelatin. MMR contains all live vaccines, chick embryo, cells from aborted babies, neomycin, sorbitol and hydrolyzed gelatin.(27)

MUMPS: I have been informed of the risk of my child developing inflammation of the testicles, joints, kidneys, and/or thyroid, and hearing impairment related to mumps. I understand that mumps is rarely harmful in childhood, and that most of the above risks occur when mumps is contracted in adolescence or adulthood.(28)

I understand that there is a Mumps vaccine which poses the following risks: contraction of mumps from the live vaccine, burning or stinging at the injection site, anaphylaxis, cough, rhinitis, fever, diarrhea, vasculitis, parotitis, orchitis, purpura, urticaria, erythema multiforme, optic neuritis, retrobulbar neuritis, syncope, encephalitis, febrile seizures, and nerve deafness.(29)

Mumps is usually given in the MMR and may cause those side effects and adverse reactions as noted in the measles section above.

Mumps vaccine is live and should not be given to pregnant women. It is cultured in chick embryos and contains sorbitol and hydrolyzed gelatin.(30)

RUBELLA (GERMAN MEASLES): I have been informed of the risk of my child developing inflammation of the brain or joints, and of the risk of birth defects (including eye defects, heart defects, deafness, mental retardation, growth failure, jaundice, and disorders of blood clotting) in infants born to mothers who contract rubella during pregnancy, related to rubella. Therefore, I understand that the greatest risk to my child may be if she never contracts rubella as a child, but when she is pregnant and it damages her unborn child. If she contract rubella in childhood, she is immune for life, and prior to the vaccine 85% of the population was immune.(31) I understand that if she is not immune as an adult, she can choose to take the vaccine prior to becoming pregnant. I understand that many of those who contract rubella have been immunized (up to 80%). (32)

Adverse reactions from the vaccine among teenage girls is 5-10% and 30% in adult women.(33) Adverse reactions include: contracting rubella from the live virus in the vaccine, burning or stinging at the site, lymphadenopathy, urticaria, rash, malaise, sore throat, fever, headache, dizziness, nausea, vomiting, diarrhea, polyneuritis, arthralgia, arthritis, local pain and inflammation, erythema multiforme, cough, rhinitis, vasculitis, anaphylaxis, syncope, optic neuritis, retrobulbar neuritis, papillitis, Guillain-Barré Syndrome, encephalitis, thrombocytopenia, purpura, and Chronic Fatigue Syndrome. (34)

Rubella is most often administered in the MMR and may cause those side effects and adverse reactions listed under measles.

Rubella is cultured on the tissue of an aborted child. This child was the 27th child aborted and tested by researchers due to exposure to rubella in a pregnant woman. It contains neomycin, sorbitol and hydrolyzed gelatin.(35)

HEPATITIS B: I have been informed of the risk of my child developing Hepatitis B viral infection which can cause chronic inflammation of the liver leading to cirrhosis, liver cancer, and possibly death. I understand that my child’s risk of developing Hepatitis B is low if I am not a carrier or infected, if my child does not engage in promiscuous sex or use drugs. I understand that there is antibiotic treatment for HepB and that most of those who contract it recover.(36) I understand that the HepB vaccine only contains strains of HepB and is not effective against HepA, C, D, E, F, or G.

I understand that the HepB vaccine has the following side effect and adverse reactions: induration, erythema, swelling, fever, headache, dizziness, pain, prutitus, ecchymosis, sweating, malaise, chills, weakness, flushing, tingling, hypotension, flu-like symptoms, upper respiratory illness, nausea, anorexia, abdominal pain and cramping, vomiting, constipation, diarrhea, lymphadenopathy, pain or stiffness in muscles and joints, arthralgia, myalgia, back pain, rash, urticaria, petechiae, sleepiness, insomnia, irritability, agitation, anaphylaxis, angioedema, arthritis, tachycardia/palpitations, bronchospasm, abnormal liver function tests, dyspepsia, migraine, syncope, paresis neuropathy, hypothesis, paresthesis, Guillain-Barré Syndrome, Bell’s Palsy, transverse myelitis, optic neuritis, multiple sclerosis, thrombocytopenia, eczema, purpura, herpes zoster, erythema modosum, alopecia, conjunctivitis, keratisis, visual disturbances, vertigo, tinnitus, earache, and dysuria.(37) The studies only followed patients for 4 days post-vaccination.
The most commonly used HepB vaccine contains thimerosal, although a relatively new release does not contain thimerosal. The vaccine also contains: aluminum hydroxide, yeast protein, and phosphate buffers.(38)

VARICELLA (CHICKENPOX): I have been informed of the risk of my child developing chicken pox which could potentially result in pneumonia, secondary skin or generalized infections, or, if caught during pregnancy, birth defects in the baby. I understand chicken pox is generally benign in children, but results in significant lost hours at work for parents. Chicken pox in adults often manifests as shingles, a chronic and painful condition. I also understand that contracting chicken pox later in life may increase my risk for herpes simplex.

Side effects and adverse reactions for the chicken pox vaccine include: contracting chicken pox from the live vaccine (27%), pain and redness at site, swelling, erythema, rash, pruritus, hematoma, induration, stiffness, upper respiratory illness, cough, irritability/nervousness, fatigue, disturbed sleep, diarrhea, loss of appetite, vomiting, otitis, diaper rash/contact rash, nausea, eye complaints, chills, lymphadenopathy, myalgia, lower respiratory illness, headache, teething, malaise, abdominal pain, other rash, allergic reactions including rash and hives, stiff neck, heat rash/prickly heat, arthralgia, eczema/dry skin/dermatitis, constipation, itching, pneunonitis, febrile seizures, and cold/canker sore.(39)

Varicella vaccine is cultured on cells from aborted babies, and guinea pig cell cultures. It contains live virus, monisodium glutamate (msg), sucrose, phosphate, processed gelatin, neomycin and fetal calf serum. (40)

HEPATITIS A (HAV): I have been informed of the risk of my child developing HAV which could potentially result in prolonged or relapsed hepatitis, but will not result in chronic hepatitis disease. (41) HAV usually causes mild “flu-like” illness, jaundice, severe stomach pains and diarrhea; and, in rare cases may result in death. Infection confers lifelong immunity. (42) I understand that the CDC admits that good personal hygiene (handwashing) and proper santitation can prevent HAV. (43)

HAV infection is spread by contaminated water or food, infected food handlers, unsanitary conditions following natural disasters, ingestion of raw or undercooked shellfish, institutionalized individuals, children not yet toilet trained, blood transfusions or sharing needles with infected people. Transmission is most likely in developing countries where sanitation is poor and infection rate of children under 5 is 90%. Fatality rate is less than .6% overall, and 70% of those in patients over 49 years, many of whom have underlying liver disease. (44) Other at-risk populations include those living on American Indian reservations and in Alaskan Native villages, homosexually active men, IV drug users, people using clotting factor concentrates and international travelers. (45)
Side effects and adverse reactions from the vaccine include: injection-site soreness, headache, fever, malaise, induration, redness, swelling, fatigue, anorexia, nausea, pruritis, rash, utricaria, pharyngitis, upper respiratory tract infections, abdominal pain, diarrhea, dysgeusia, vomiting, arthralgia, elevated cratine phosphokinase, myalgia, lymphadenopathy, hypertonic episodes, insomnia, photophobia, and vertigo. (46)
Aborted fetal tissue is an ingredient in the Havrix® Hep A vaccine, as is formaldehyde, aluminum hydroxide and 2-phenozyethanol.(47)

There is currently a combination Hep A and B vaccine, Twinrix®, being tested in the UK. (48) Twinrix is grown in human cell cultures, contains 2-phenoxyethanol, neomycin sulfate, polysorbate, tromentamol and formaldehyde. (49)

PNEUMOCOCCAL: I have been informed of the risk of my child developing pneumococcal disease which could result in meningitis, blood infection, pneumonia and/or ear infections. Iunderstand studies indicate that this vaccine may only decrease ear infections by 9%, and only result in a 20% reduction in chronic ear infections and ear tube insertion in that group.

I understand that my child has a 7.5:5,000 chance of deveoping this disease if he or she is under age 2 and a 1:5000 chance of developing it if over age 2. Risk factors for developing this disease are: immunoglobulin deficiency, nephrotic syndrome, Hodgkin’s disease, congenital or acquired immunodeficiency, some upper respiratory infections, splenic dysfunctions, splenectomy or organ transplant. This vaccine (PCV) was originally marketed for immunocompromised children. (50) This vaccine is contraindicated to children with thrombocytopenia, coagualtion disorders, or sensitivity to diphtheria toxoid.(51)

Possible side effects and complications from the vaccine include: erythema, induration, tenderness, interference of limb movement, inflamation, fever, irritability, drowsiness, restless sleep, decreased appetite, vomiting, diarrhea, fussiness, rash, hives, bronchitis, asthma, pneumonia, otitis media (ear infection), sepsis, seizure, anaphylaxis and death.(52) Recipients were followed for 3 days and almost 10% of the subjects made a visit to the emergency room in the follow-up period. There were 8 cases of SIDS in the 17,066 subjects involved in the trial.(53) Note: Children in the studies’ control group received another experimental vaccine, so there have been no trial studies done with children who received no vaccine.(54)

Prevnar contains .125 mg of aluminum sulfate, protein polysaccharides from 7 strains of strep. pneumoniae bacteria, diphtheria toxin, casamino acids, yeast extract. Studies indicate that it may interfere with the safety and efficacy of other vaccines.(55)

FLU: I have been informed of the risk of my child developing influenza, which could result in hospitalization for respiratory complications, pneumonia and death. I understand less than 175 people died from the flu in the US during 2003. I understand that there is no guarantee that the flu strains chosen for this year will be the flu strains that are active this year. I understand that from 1999 - 2003, 70 - 80% of the sniffles, fevers, and body aches did not test positive for influenza regardless of the flu strain used.
The most common reactions to injected flu vaccines, which begin within 12 hours of vaccination and can last several days are: fever, fatigue, painful joints and headache. The most serious reaction that has been associated with flu vaccine is Guillain-Barré Syndrome (GBS), which occurs most often within two to four weeks of vaccination. GBS is an immune mediated nerve disorder characterized by muscle weakness, unsteady gait, numbness, tingling, pain and sometimes paralysis of one or more limbs or the face. Recovery takes several months and can include residual disability. Less than 5 percent of GBS cases end in death. Brain and nerve disorders such as encephalopathy, optic neuritis, partial facial paralysis, and brachial plexus neuropathy as well as vasculitis also have been reported following the flu vaccine, although a definite causal relationship has not been established. (56) A tenfold increase in Alzheimer’s disease exists for those who receive the flu vaccine five years in a row. (57)

FluMist: Reported adverse effects in children include runny nose, nasal congestion, cough, sore throat, headache, irritability, decreased activity, fever, chills, muscle aches, and vomiting. In adults the most common side effects were runny nose, cough, sore throat, headache, muscle aches, fever, chills and tiredness or weakness. Other adverse events that occurred in children were abdominal pain, asthma, bronchitis, conjunctivitis, viral syndrome, otitis media (middle ear infection), and wheezing or shortness of breath.(58)

Fluzone is propagated in chick embryos. It contains formaldehyde, sucrose, polyethylene glycol, sodium phosphate, salt and thimerosal.(59) Fluvirin is prepared in chicken eggs and contains thimerosal, neomycin, polymyxin, and phosphate-buffered saline. (60)
FluMist is a live vaccine propagated in chicken eggs, and contains potassium phosphate, sucrose (table sugar) and monosodium glutamate (MSG). (61)

HUMAN PAPILLOMAVIRUS (HPV): I have been informed of the risk of developing HPV. HPV is a sexually-transmitted disease that can cause genital warts, and it’s most severe stage, cervical cancer. I understand that there are more than 100 forms of HPV and that the currently available vaccine only covers four of the strains; current screening for HPV looks for 13 ‘high risk’ strains. The CDC estimated that 20 million people in the US had HPV and many strains cause no harm. (62) I understand current research shows that most women will quickly clear the infection on their own, and very few will develop pre-cancerous or cancerous lesions. Use of the vaccine will not cure HPV infection, and the duration of the longest HPV vaccine studies covered less than 50% of the time it takes to progress from CIN 2 or 3 levels to cervical cancer, so 100% efficacy cannot realistically be proven. (63) HPV vaccination does not take the place of routine Pap screens. (64)

The most common reactions to the HPV vaccines were pain, swelling, redness and itching at the injection site. More than 90% of vaccine test subjects and more than 85% of subjects receiving the aluminum-containing placebo experienced at least one of these reactions. (65) Other reactions from the vaccine included: systemic fever, nausea, nasopharyngitis, dizziness, diarrhea, vomiting, myalgia, cough, upper respiratory tract infection, malaise, arthralgia, insomnia and nasal congestion. More severe reactions included headache, gastroenteritis, appendicitis, pelvic inflammatory disease, asthma, pulmonary embolism, sepsis, arrhythmia, juvenile arthritis, rheumatoid arthritis, lupus, arthritis and reactive arthritis. There were also statistically higher levels of birth defects in women who got pregnant within 30 days of receiving the vaccine and in more than 30 cases of birth defects in women who became pregnant after 30 days from either Gardasil® or the aluminum-containing placebo. (66)

Gardasil® is currently the only HPV vaccine approved for use and contains 225mcg of aluminum hydroxyphosphate sulfate, sodium chloride, L-histidine, polysorbate 80, sodium borate, water, and proteins from HPV strains 6, 11, 16 and 18 grown in yeast fermentation medium. (67)

Reference List
1. M. Burnet and D. White, The Natural History of Infectious Disease (Cambridge, 1972), p. 16.
2. Strebel, et al, “Epidemology in the U.S. One Decade After the Last Reported Case of Indigenous Wild Virus Associated Disease,” Clinical Infectious Diseases, (Center for Disease Control, February 1992), pp. 568-79.
3. Physician’s Desk Reference (PDR), 50th Edition; Medical Economics, 1996, p. 1388-1390.
4. Ibid, p. 885-886 and 891-892.
5. J. Butel, et al; “Molecular Evidence of Simian Virus 40 Infections in Children”, The Journal of Infectious Diseases ; September 1999;180:884-887.
6. PDR, 50th Edition, p. 872-875.
7. Ibid.
8. Ibid.
9. Richard Moskowitz, M.D., “Immunizations: The Other Side,” Mothering, (Spring1984),p. 34.
10. Immunization: Survey of Recent Research, (United States Department of Health and Human Services, April 1983), p. 76.
11. “Nature and Rates of Adverse Reactions Associated with DPT and DT Immunizations…,” Pediatrics, Volume 68, No. 5 (November 1981).
12. Walene James, Immunization the Reality Behind the Myth, (South Hadley, Massachusetts: Bergin & Garvey, 1988), p. 14.
13. W.C. Torch, “Diptheria-pertussis-tetanus (DPT) immunization: A potential cause of sudden infant death syndrome (SIDS),” (Amer. Academy of Neurology, 34th Annual Meeting, Apr 25 - May 1, 1982), Neurology 32(4), pt. 2.
14. PDR, p. 875-879 and 892-895.
15. Ibid.
16. Robert Mendelsohn, M.D., How to Raise A Healthy Child…In Spite of your Doctor (Chicago: Contemporary Books, 1984), p.223.
17. Ibid. 244-246
18. Isaac Golden, Ph.D., Vaccination? A Review of Risks and Alternatives, (Geelong, Victoria, Australia: Arum Healing Centre, 1991), p. 31
19. Richard Moskowitz, M.D., “Immunizations: The Other Side,” Mothering, (Spring1984),p. 34.
20. Isaac Golden, Ph.D., Vaccination? A Review of Risks and Alternatives; p. 71
21. R. Mendoholson; How to Raise a Healthy Child; p. 217.
22. John Frank Jr., M.D., et al. “Measles Elimination - Final Impediments,” 20th Immunization Conference Proceedings, May 6-9, 1985, p. 21.
23. Infectious Diseases (January 1982), p. 21.
24. PDR, p. 1610-1611.
25. DR, p. 1687-1689.
26. Sara Solovitch, “Do vaccines spur autism in kids?”, San Jose Mercury News, 5/25/99.
27. PDR, p. 1687-89, 1610-1611.
28. Richard Moskowitz, M.D., “Immunizations: The Other Side,” Mothering, (Spring1984),p. 35.
29. PDR, 1708-1709.
30. Ibid.
31. R. Mendoholson; How to Raise a Healthy Child; p. 218.
32. Dr. Beverley Allan, Australian Nurses Journal, (May 1978).
33. Hannah Allen, Don’t Get Stuck: The Case Against Vaccinations…, (Oldsmar, FL: Natural Hygiene Press, 1985), p. 144.
34. DR, p. 1697-1699.
35. Ibid and Attenuation Of RA 27/3 Rubella Virus in WI-38 Human Diploid Cells; Amer J Dis Child vol 118 Aug 1969 and Studies of Immunization With Living Rubella Virus ; Arch J Dis Child vol 110 Oct 1965.
36. John Hanchette, “Safety of controversial hepatitis B vaccine at center of debate” Gannett News Service, 5/18/99.
37. PDR, p. 1744-1747, 2482-2484.
38. Ibid.
39. PDR, p. 1762-1765.
40. Ibid.
41. CDC Viral Hepatitis A - Fact Sheet, 9/29/00; http://www.cdc.gov/ncidod/diseases/hepatitis/a/fact.htm
42. CDC Hepatitis A Vaccine Vaccine Information Statement; 8/25/98
43. CDC Hepatitis A Facts, 11/16/00
44. Mosby’s GenRX®, 10th Ed., Hepatitis A Vaccine (003158) as posted on MDConsult website
45. CDC Hepatitis A Vaccine Vaccine Information Statement; 8/25/98 and CDC Hepatitis A Vaccine Vaccine Information Statement; 8/25/98
46. Mosby’s GenRX@, Hepatitis A Vaccine
47. Ibid.
48. “Combined hepatitis A/B vaccine offers fast protection,” Reuters Health, 4/12/00
49. Vaccines and Their Ingredients, 6/24/99; http://www.909shot.com
50. Michael Horwin, MA; “Prevnar: A Critical Review of a New Childhood Vaccine” 9/19/00.
51. Prevnar package insert, Wyeth Lederle, 2/17/00
52. Ibid.
53. Horwin; “Prevnar: A Critical Review”
54. Dr. Erdem Cantekin, Ph.D.; “Pneumocaoccal Vaccine and Otitis Media”, NVIC’s 2nd Intl. Public Conference, 9/8/00.
55. Horwin; “Prevnar: A Critical Review”
56. Physician’s Desk Reference (PDR), 53rd Edition; Medical Economics, 1999, p. 2326, 3464
57. Dr. Russell Blaylock, MD; “The Truth Behind the Vaccine Coverup” 9/22/04; http://www.mercola.com/2004/sep/22/blaylock_vaccine_coverup.htm
57. Fluzone 2003-2004 Formula, Aventis Product information as of July 2003
58. Dr. Sherry Tenpenny, DO, “FluMist Vaccine: Nothing to Sneeze At!” 10/23/2003; http://www.nmaseminars.com .
59. Influenza Virus Vaccine Live, Intranasal FluMist 2003-2004 Formula, Package Insert (Circular) June 16, 2003.
60. “New Preservative Free Flu Vaccine Approved,” http://www.accessdata.fda.gov/psn/transcript.cfm?show=10
61. Dr. Sherry Tenpenny, DO, “FluMist Vaccine: Nothing to Sneeze At!”
62. CDC HPV Fact Sheet, http://www.cdc.gov/std/HPV/STDFact-HPV.htm
63. Dr. Clayton Young, MD, FACOG, “OBGYN Against ACIP HPV Vaccine Decision,” 6/27/2006
64. CDC HPV Fact Sheet, http://www.cdc.gov/std/HPV/STDFact-HPV.htm
65. Merck Professional Privider Information Sheet: Gardasil® [Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recominant Vaccine. http://www.Merck.com
66. Daron G Ferris, “Facing the Future: The Impact of HPV Vaccination on Adolescent Health,” and “An Update of Clinical Trial Results With Preventative HPV Vaccines” http://www.medscape.com/viewprogram/5334
67. Merck Professional Privider Information Sheet: Gardasil® [Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recominant Vaccine. http://www.Merck.com

Complied by Kathryn E. Rateliff, CCD, CCM, CCCE, GSM, PE, BFE
October, 1999 and most recently revised August 10, 2006
Questions and comments can be addressed to her at: titus2ed@aol.com.

01 September, 2008

Suicide Risk Increases With Medication

Increased rates suicide and violent behavior have been linked to anti depressant medication. Federal drug regulators are now investigating links with other medications to suicide. Among the drugs being investigated are an asthma medication, drugs for controlling seizures, and even a substance used to assist those who want to quit smoking.

Drug companies insist that a cause and effect relationship has not been proven. During clinical trials, no suicides were reported. Doctors hold a concern that worries over suicide risk may cause their patients to think twice about taking these medications. However, families who have experienced the sudden, unexpected loss of a family member feel that they should have been given the information to make an informed choice.

Recently, the FDA pulled together a panel of scientific advisors to study 210 clinical trials of eleven anti seizure drugs. The panel found a ‘slight’ increase in incidents of suicidal thoughts or behavior. The survey did not indicate which drugs were more or less likely to foster risk. Even a two out of a thousand increase can result in large numbers of people at risk when the drugs are prescribed to millions of people. Certainly, the families directly effective find no solace in how ‘small’ those numbers seem.

The FDA is considering how to communicate the risk to patients without causing alarm. The panel did not advise putting a strong warning on the drugs’ labels.

Compare these numbers to the two out of a thousand whose lives are improved by certain blood pressure medications which are avidly prescribed throughout the world. It would seem the medical companies find those numbers significant on other fronts.

A group at Columbia University developed a method to assess the suicide risks of drugs. They collect and analyze suicidal thoughts and actions of people enrolled in clinical trials. The FDA funded the research, but only requires use of assessments on a case-by-case basis. The oversight is curious to many since its use could possibly help identify risks before a medication goes on the market.

"Whether or not any of these drugs cause suicidal thoughts and behavior is the critical question we need to answer; up to now, we have not answered that," said Kelly Posner, a Columbia researcher who led the effort to develop the screening system. "Debunking false notions of risk is just as important to the public health as knowing about risks that exist."

Behavior can be affected by chemical changes in the brain. This is the basis for prescription of drugs for depression, anxiety, or other psychiatric illnesses. Other drugs can also affect the brain. Little is known about these effects.

The brain is protected by a semi permeable membrane. Most chemicals are prevented from entering the brain in this way. Yet, others are allowed in differing amounts.

Psychiatric drugs, of course, cross the blood-brain barrier. Presumably, the same is true of anti-seizure medication. Other drugs may pass the barrier in limited amounts. However, few studies are done on the interaction of drugs with the blood-brain barrier. Many of those which have been done are limited to animal studies. Such information can be useful, but is limited in its relevance to human brains. Fewer studies, still, have been done on what affects those chemicals have once they come in direct contact with the master control center of the human body.

Regardless of the purpose for which a drug is prescribed, there is potential for psychiatric side effects if it passes the blood-brain barrier. Drugs for asthma, weight control, quitting smoking, and even certain heart medications may have potential for changing a person’s behavior and mood.

A list of some prescription medications for which concerns have been raised involving suicidal thoughts and actions:

• All antidepressants: Drugs such as Prozac, Paxil, Wellbutrin and Zoloft carry required warnings that the medications can increase suicidal thinking and behavior in some children, adolescents and young adults.

• Anticonvulsives: Drugs such as Depakote, Lyrica and Neurontin are used to treat seizures and other conditions. A recent FDA analysis found a small increased risk of suicidal thinking and behavior. An advisory panel recommended against applying the agency's strongest warning to the drugs.

• Chantix: The FDA is investigating whether the smoking cessation drug triggers psychiatric symptoms.

• Singulair: The FDA is investigating whether the drug for asthma and allergies can prompt suicidal thoughts.

• Accutane: The acne drug carries a warning that it may cause suicidal thoughts and behavior in rare cases.

Increasing reports of family trauma due to personality changes and otherwise unexplained suicides indicate that many questions have yet to be answered about the full range of effects highly targeted synthetic chemicals have on our overall health. No wonder more and more people are looking to time-tested dietary and herbal prevention and remedies.


Resources:

http://news.yahoo.com/s/ap/20080831/ap_on_go_ot/med_drugs_suicide;_ylt=Agwvy5wwqd1PsPIQTaxNEEKs0NUE

http://news.yahoo.com/s/ap/20080831/ap_on_go_ot/med_drugs_suicide_list_1