Showing posts with label dementia. Show all posts
Showing posts with label dementia. Show all posts

03 February, 2009

Fermented Soy is Only Soy Food Fit for Human Consumption

by Barbara Minton, Natural Health Editor

(NaturalNews) Writings about the soybean date back to 3000 B.C., when the Emperor of China listed the virtues of soybean plants for regenerating the soil for future crops. His praises centered on the root of the plant, not the bean. These ancient writing suggested that the Chinese recognized the unfitness of soybeans for human consumption in their natural form. Now 5000 years later, we are once again catching on to the anti-nutritive qualities of the soybean, and realizing that the only soybean worth eating is one that has been fermented.

The key to releasing the nutrients of the soybean has been known for thousands of years

About 1000 B.C. some smart person in China discovered that a mold, when allowed to grow on soybeans, destroyed the toxins present and made the nutrients in the beans available to the body. This process became known as fermentation and led to the creation of the still popular foods tempeh, miso, and natto.

A few centuries later, a simpler process was developed to prepare soybeans for consumption. After lengthy soaking and cooking, the beans were treated with nigari, a substance found in seawater. The end product was tofu. During the Ming dynasty, fermented soy appeared in the Chinese Materia Medica as a nutritionally important food and an effective remedy for diseases.

Unfermented soybeans contain potent anti-nutrients

In their natural form, soybeans contain phytochemicals with toxic effects on the human body. The three major anti-nutrients are phytates, enzyme inhibitors and goitrogens.

These anti-nutrients are the way nature protects the soybean plant so that it can live long enough to effectively reproduce. They function as the immune system of the plant, offering protection from the radiation of the sun, and from invasion by bacteria, viruses, or fungi. They make the soybean plant unappetizing to foraging animals. All plants have some anti-nutrient properties, but the soybean plant is especially rich in these chemicals. If they are not removed by extensive preparation such as fermentation or soaking, soybeans are one of the worst foods a person can eat.

Unfermented soy has been linked to digestive distress, immune system breakdown, PMS, endometriosis, reproductive problems for men and women, allergies, ADD and ADHD, higher risk of heart disease and cancer, malnutrition, and loss of libido.

Groups most at risk of experiencing negative effects from the anti-nutrient properties of soy are infants taking soy baby formula, vegetarians eating a high soy diet, and mid-life women going heavy on the soy foods thinking they will help with symptoms of menopause.

Soybeans contain high levels of phytates

All legumes contain phytate (also known as phytic acid) to some extent, but the soybean is particularly rich in this anti-nutrient. Phytate works in the gastrointestinal tract to tightly bind minerals such as zinc, copper, iron, magnesium and calcium. It has a particularly strong affinity for zinc, a mineral that supports wound healing, protein synthesis, reproductive health, nerve function, and brain development. It is believed that people living in developing countries are shorter than those in developed countries because of zinc deficiency caused by eating too many legumes. There is also evidence that mental development can be negatively impacted by a diet high in phytate.

In most legumes such as other varieties of beans, soaking is enough to break down most of the phytate content. However the soybean requires that the enzymes be released in the fermentation process to reduce its phytate content to the point where it becomes fit for consumption. This means that fermented soy foods like miso and tempeh have the lowest levels of phytate and are the best choices for anyone wishing to eat soybean products. Tofu is also a good choice, as long as care is taken to replenish loss nutrients.

Whole soybeans, soy milk, soy chips, soy protein isolates, soy flour and all the other myriad of products made from processed soybeans and advertised as health foods have much higher levels of phytate and are not worth eating.

Unfermented soy products are rich in enzyme inhibitors

When food is eaten, digestive enzymes such as amylase lipase and protease are secreted into the digestive tract to help break it down and free nutrients for assimilation into the body. The high content of enzyme inhibitors in unfermented soybeans interferes with this process and makes carbohydrates and proteins from soybeans impossible to completely digest. When foods are not completely digested because of enzyme inhibitors, bacteria in the large intestine try to do the job, and this can cause discomfort, bloating, and embarrassment. Anyone with naturally low levels of digestive enzymes such as elderly people would suffer the most from the enzyme inhibiting action of soy.

Soybeans can block production of thyroid hormone

Soybeans have a high content of goitrogens, substances that can block the production of thyroid hormone as well as cause goiter formation. Low thyroid activity plagues women in America, particularly middle-aged women. Thyroid hormone stokes the cellular furnaces, known as mitochrondia. When thyroid production is low, energy levels as well as body heat are also low. Low thyroid level is what makes old people move so slowly and seem like every action is a huge chore. Low thyroid means the action of the heart is reduced, resulting in lack of oxygen to the cells, a prime condition for cancer.

Genistein, an isoflavone found in soybeans, can also block thyroid production. Phytate can accentuate these effects because it binds up zinc and copper, leaving little of these important minerals available to make thyroid hormone.

A transport protein called GLUT1 is shut down by genistein. This protein sends glucose into the cells where it is used to generate energy. Slowing the transport of glucose means less energy production not only of thyroid hormone, but of every other action in the body.

Another way in which soy isoflavones reduce energy in the body is by inhibiting tyrosine kinases, enzymes involved in the transfer of energy from one molecule to another. These enzymes drive cell division, memory consolidation, tissue repair, and blood vessel maintenance and regeneration.

It is this action of regulating cell division that made genistein a popular substance for fighting cancer. When research on this anti-cancer effect of genistein became know, the soy industry feverishly developed products that would appeal to Western women looking for genistein. In the middle of all this excitement, little attention was paid to how the energy reducing effects of genistein lowered cellular energy in normal cells.

The benefits of genistein come at a high cost

Women have been encouraged to use high genistein soy products to alleviate symptoms of menopause and as a guard against bone loss and breast cancer. But given the full range of effects of genistein in the body, high consumption could result in age-related memory loss. Commercial soybean products offer genistein levels as high as 20 to 60 mg per serving. Asians are presented as an example of the benefits of eating soybean products because their incidence of breast cancer and osteoporosis is low. However, the Asian diet of fermented soybean products such as miso and tempeh includes only around 5 mg of genistein a day.

Genistein slows the growth of blood vessels to tumors, another action that makes it popular as a cancer fighter. However, it has the same effect on blood vessels serving normal cells. Eating a regular diet high in genistein could result in the starvation of healthy blood vessels, resulting in a reduced supply of oxygen to cells, setting up a cancer promoting situation.

In a graphic example of how genistein slows cellular energy, a study found that eating high levels of it slowed hair growth by 60 to 80 percent

A decade ago a study of 8,000 Asian men showed that those consuming the highest amounts of tofu had smaller brain size and nearly three times the rate of senile dementia as those who ate the lowest amounts. These results suggest that eating foods high in isoflavones such as soy protein isolates may accelerate the aging of the brain.

Fermentation releases nutrients and transforms soybeans into nutritious food

People filling up their shopping carts with raw or cooked soybeans, soy milk, and other non-fermented soybean products do not realize that the isoflavones they contain will not be available to their bodies. Most of the isoflavones in soy products are bound to carbohydrate molecules called glucosides. In this form genistein is actually called genistin. It is fermentation that transforms genistin into genistein. Many products in the U.S. do not distinguish between genistin and genistein on their labels.

Even with fermented soy foods, a little goes a long way. The nutrients found in miso, tempeh, and natto can be beneficial in the moderate amounts found in the typical Asian diet, but have the potential to do harm in higher amounts. In China and Japan, about an ounce of fermented soy food is eaten on a daily basis.

When fermented soy foods are used in small amounts they help build the inner ecosystem, providing a wealth of friendly microflora to the intestinal tract that can help with digestion and assimilation of nutrients, and boost immunity.

Dr. John Lee, author of several books on the health of women, recommended that women wishing to consume soy production eat only miso, tempeh, natto. Tofu can also be eaten provided it is accompanied by fish or some other protein source and some seaweed or kelp to replenish bound minerals. Eating small amounts of these foods will provide the cancer protective effects of genistein without causing the other potential problems of genistein. Dr. Lee recommended avoiding genistein and isoflavone supplements, and soy protein isolates.

Sources:

Dr. John Lee, What Your Doctor May Not Tell You About Breast Cancer: How Hormone Balance Can Help Save Your Life, Warner Books.

How Fermenting Takes the Allergy Out of Soy and Other Foods.

17 October, 2008

Moderate Alcohol Consumption Shrinks Brain

We have been told that moderate use of alcohol is good for the heart. However, reports from the Framingham Study show that moderate to heavy alcohol use is associated with damage to brain tissue. Such damage to the brain may lead to higher risk of stroke or dementia.

The Framingham Study began in 1948 to follow the residents of Framingham, Massachusetts and their offspring. The study is now following a third generation of participants. The goal of the study is to follow people over a long period of time, documenting their state of cardiovascular disease.

At the beginning of the study, subjects have no evidence of heart disease. The subjects are put through a series of tests every two years. Over time, medical records are analyzed to determine risk factors for cardiovascular disease. Much of the information published about risk factors for heart disease and stroke comes from this study.

The American Academy of Neurology presented evidence in 2007 from Wellesley College, Massachusetts. Carol Ann Paul M.S. and her associates reported that even moderate amounts of alcohol are associated with brain atrophy and possibly an increased risk of dementia or stroke.

Researchers performed MRI scans on 1,839 people aged 34 to 88 to compare the volume of brain tissue to their cranial size. Subjects were classified as non-drinkers, former drinkers, low drinkers (1 to 7 drinks per week), moderate drinkers (8 to 14 drinks per week), or high drinkers (more than 14 drinks per week). Brain shrinkage numbers increased by .25 percent as amount and frequency of drinking increased. People who consumed more than 14 drinks per week had brains which averaged 1.6 percent smaller than those who did not drink alcohol. For women, especially those in their 70's, the change was more dramatic than for men. Researchers speculated that the differences may be associated with the smaller body mass of women. In addition, those who had a longer history of heavy alcohol consumption also had more brain atrophy. The team noted that men were more likely to become heavy drinkers than women.

The same group reported again in 2008 in the Journal of the American Medical Association: "The public health effect of this study gives a clear message about the possible dangers of drinking alcohol," the authors write. "... This study suggests that, unlike the associations with cardiovascular disease, alcohol consumption does not have any protective effect on brain volume.” They suggest further, longer term studies to determine the full impact of these findings.

In general, brain volume decreases with age at an estimated rate of 1.9 percent every ten years. At the same time white matter lesions replace grey matter. Lower brain mass and white lesions are associated with problems in movement, thinking, learning, and memory.

A 2006 study from the Erasmus Medical Center in Rotterdam observed that people who developed dementia decreased in brain volume between 5 and 17 percent during the eight year study. Those who were diagnosed with Alzheimer’s had a decrease up to 40 percent. People with atrophy in parts of the brain known as the amygdala and hippocampus had the highest risk of developing dementia or Alzheimer's disease.

The accelerated loss of grey matter under the influence of alcohol is worth considering before you down that second (or third) serving of spirits.

Resources

JAMA and Archives Journals (2008, October 14). Drinking Alcohol Associated With Smaller Brain Volume. ScienceDaily. Retrieved October 16, 2008, from http://www.sciencedaily.com/releases/2008/10/081013171421.htm

Johns Hopkins University Bloomberg School Of Public Health (2003, December 5). Moderate Alcohol Consumption Linked To Brain Shrinkage. ScienceDaily. Retrieved October 16, 2008, from http://www.sciencedaily.com/releases/2003/12/031205052952.htm

American Academy of Neurology (2007, May 3). Drinking Heavy Amounts Of Alcohol Shrinks Your Brain. ScienceDaily. Retrieved October 16, 2008, from http://www.sciencedaily.com/releases/2007/05/070502172317.htm

http://www.abstracts2view.com/aan2007boston/html/P05.030.html

http://www.redorbit.com/news/health/347670/reduced_brain_volume_may_predict_dementia/index.html

01 March, 2008

Scientific Revelation: Age Related Decline Is Not Inevitable

A Dutch woman decided to will her body to science when she was 82 years old. When she turned 111, she contacted the researchers, worried that she was too old to be of interest to them. On the contrary, they assured her, because of her age, they were especially interested in her.

Over the next four years, she submitted to testing twice. The results showed her to be above average, even for people aged 60 to 80 years of age. There were essentially no signs of cognitive decline or memory loss.

Gert Holstege, a neuroscientist at the University Medical Center Groningen, in The Netherlands examined her body after she died at 115 years of age. The results are reported in the August issue of the journal Neurobiology of Aging.

To the surprise of the examiners, the woman’s brain showed no sign of Alzheimer’s. They found no signs of atherosclerosis, a narrowing of the arteries. Very few brain abnormalities were evident. almost no deposits of so-called beta-amyloid, which are characteristic in Alzheimer's brains. Other abnormalities present, including "neurofibrillary tangles," were too mild to cause significant mental impairment. In fact, the number of brain cells she retained was similar to that expected in healthy people between 60 and 80 years old.

Scientists were amazed at these findings, because they showed that Alzheimer’s and dementia are not inevitable as people age.

On the Spanish island of Minorca, a man recently died at the age of 114. Reports speak of him riding his bicycle to tend to the family’s orchards until he was 102. He is survived by a brother, who is 101, a nephew who is 85, and two daughters, aged 81 and 77. All seem to live an active health-filled lifestyle.

Scientists tested the family’s DNA for two markers associated with healthy bones and longevity. The markers were not found. Gil Atzmon, of the Albert Einstein College of Medicine in New York informs us that some 10 to 20 genes have been identified as related to longevity thus far.

These findings lead scientists to believe that longevity may be more complicated than a single gene, or group of genes.

As of yet, no particular diet or lifestyle has a proven association with longevity. Yet some clues have been uncovered that point us in the direction of factors which can contribute to a longer, healthier life.

In the 1930's, Cornell University researchers found that rats fed a lower calorie diet than their litter mates lived 40 percent longer. The increased life span occurred regardless of the age of the rats at the time of their diet change.

A mother’s nutrition while she is pregnant and nursing can have a profound effect on her offspring’s life span. Scientists at Cambridge University in England found that mice fed a high protein diet during pregnancy and a low protein diet while nursing had pups that lived fifty percent longer than those whose diets were reversed.

Happily married couples tend to live longer, claims a study from the University of Chicago. Linda Waite reported that married men were found to live, on average, 10 years longer than non-married men, and married women lived about four years longer than non-married woman.

A May 2, 2006 article in the American Journal of Medicine reports that walking is a factor in health and longevity. In their study, patients in their 70's who were in good health were challenged to walk a quarter mile. Those who completed the course were more likely to survive the next six years without disability. Those who walked slower were at higher risk of death and disability than the faster walkers, but still ahead of those who could not finish.

As a matter of fact, additional studies show that walking or other exercise three or more times a week is a hedge against Alzheimer’s.

Staying mentally and physically active throughout life is the best way to keep the mind sharp.
Individuals with high mental stimulation had a reduced risk of Alzheimer's disease and other forms of dementia by nearly half by building and maintaining a reserve of stimulation. Another study showed that after five weeks of memory-based exercise, participants increased brain chemistry markers in a direction that was opposite to that seen in Alzheimer's. The change was concentrated in the hippocampus, one of the first brain regions to be affected in dementia.

Currently, there are more than 80,000 Americans 100 years of age or older, according to the U.S. Census Bureau. That number is expected to rise to more than 580,000 centenarians by 2040. The hope is that these centenarians might live long, healthy, and happy lives.

References:

((http://www.livescience.com/health/08060...)

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